What is Lortab?
Lortab 5/325mg is a prescription medicine used to relieve moderate pain.
It combines:
- Hydrocodone – a strong opioid pain medicine
- Acetaminophen (325mg) – a medicine that helps reduce pain and fever
This combination works better than many single-ingredient pain medicines. Doctors often prescribe Lortab when regular pain relievers are not strong enough.
What Is Lortab Used For?
Lortab 5/325mg may be prescribed for:
- Pain after surgery
- Injury pain
- Dental pain
- Muscle pain
- Joint pain
- Short-term severe discomfort
How Lortab Works
Hydrocodone
Hydrocodone changes how the brain responds to pain signals.
Acetaminophen
Acetaminophen helps increase pain relief and may reduce fever.
Together, these medicines provide faster, stronger pain relief.
Benefits of Lortab 5/325mg
This medicine may help:
- Relieve moderate pain quickly
- Improve comfort during recovery
- Reduce pain after surgery or injury
- Help patients rest more comfortably
- Support short-term pain management
How to Take Lortab 5/325mg
Always follow your doctor’s instructions when taking this medicine.
Usual Dosage
- Usually taken every 4 to 6 hours if needed for pain.
The dose may depend on:
- Your pain level
- Your medical condition
- How your body reacts to treatment
Important Dosage Warnings
- Do not take extra doses
- Do not change your dosage without medical advice
- Avoid taking other medicines that contain acetaminophen
Possible Side Effects
Common Side Effects
Some people may experience:
- Sleepiness
- Dizziness
- Nausea
- Vomiting
- Constipation
- Dry mouth
Serious Side Effects
Get emergency medical help if you notice:
- Trouble breathing
- Slow breathing
- Severe confusion
- Extreme drowsiness
- Skin rash or swelling
- Signs of liver problems
Important Safety Warnings
Lortab contains an opioid medicine and may become habit-forming.
Important Things to Know
- Misuse may cause addiction or overdose
- Long-term use may increase the risk of dependence
- Do not take alcohol while taking this medicine
- Avoid combining with other acetaminophen medicines
- Use only under medical supervision
Safety Precautions
For safe use:
- Take only as prescribed
- Do not share this medicine with anyone
- Keep away from children
- Avoid driving if you feel sleepy
- Store in a cool and dry place
Who May Need Lortab 5/325mg?
Doctors may prescribe this medicine for patients who:
- Have moderate pain
- Need stronger pain relief
- Did not get enough relief from regular pain medicines
- Need short-term opioid pain treatment






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